Isotopically Labeled Compounds
Medchemexpress LLC Arachidic acid-d39 | 39756-32-6 | 351.77 | 10 MG
Arachidic acid-d39 is the deuterium labeled Arachidic acid (HY-W004260), also known as Eicosanoic acid. It is a long-chain saturated fatty acid found in plasma phospholipid, fish, cannabis, and other plant oils. This compound can be used for anti-cancer drug delivery research when conjugated with Chitosan oligosaccharide.
- Used as a tracer.
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes are incorporated into drug molecules as tracers for quantitation.
- Deuteration affects pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Phenacetin-13C | 72156-72-0 | 99.9% | 25 MG
Phenacetin-13C is a 13C labeled version of Phenacetin, also known as Acetophenetidin. It is a non-opioid analgesic and antipyretic agent that acts as a selective COX-3 inhibitor. It is utilized as a probe for cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats. Stable heavy isotopes, such as carbon-13, are incorporated into drug molecules for quantitation during drug development, with deuteration also having potential impacts on pharmacokinetic and metabolic profiles.
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Selective COX-3 inhibitor
- Probe for cytochrome P450 enzymes CYP1A2
- Features a stable heavy isotope (carbon-13) for quantitation during drug development
Medchemexpress LLC L-Lysine-13C6,15N2 hydrochloride | 1200447-00-2 | 190.59 | 100 MG
L-Lysine-13C6,15N2 hydrochloride is a stable isotope-labeled L-Lysine hydrochloride. It is an essential amino acid known for its various benefits, including aiding in treating herpes, enhancing calcium absorption, mitigating diabetes-related illnesses, and promoting gut health.
- Can be used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Yohimbine-d3 | 133146-00-6 | 99.0% | 357.46 g/mol | C21H23D3N2O3 | 5 MG
Yohimbine-d3 is the deuterium-labeled analogue of yohimbine intended for use as a tracer or internal standard in analytical and mass-spectrometry workflows. It provides a mass-differentiated reference to support accurate quantitation and method validation.
Medchemexpress LLC Tiopronin-13c,d3 | 1189695-13-3 | ≥98% | 1 MG
Tiopronin-13C,d3 is a deuterium labeled form of Tiopronin. Tiopronin is known as a diffusible antioxidant, an antidote for heavy metal poisoning, and a radioprotective agent. This compound can help control the rate of cystine precipitation and excretion, showing potential for use in treating conditions like cystinuria, rheumatoid arthritis, and various hepatic disorders.
- Deuterium labeled Tiopronin
- Functions as a diffusible antioxidant
- Acts as an antidote to heavy metal poisoning
- Serves as a radioprotective agent
- Shows potential for cystinuria, rheumatoid arthritis, and hepatic disorders
Medchemexpress LLC Nicardipine-d3 hydrochloride | 1432061-50-1 | MFCD30747912 | 99.7% | 519.00 | C26H27D3ClN3O6 | 1MG
Nicardipine-d3 hydrochloride is the trideuterated hydrochloride salt of nicardipine provided as a research-grade isotopically labeled reference standard for analytical chemistry and mass spectrometry applications. It is intended for use as an internal standard in LC-MS method development, quantitation, and related laboratory studies. For research use only.
- Deuterium-labeled analogue suitable as an internal standard.
- High isotopic enrichment to improve mass-spectrometry accuracy.
- High chemical purity appropriate for analytical workflows.
- Hydrochloride salt form for improved stability and handling.
- Available in milligram quantities for trace-level standard preparation.
Medchemexpress LLC Procymidox-d5 | >95.0% | 289.17 | C13H6D5Cl2NO2 | 5 MG
Procymidox-d5 is the deuterium-labeled analogue of procymidone supplied as an isotope-labeled reference for analytical workflows. It is intended for use as a tracer or internal standard to improve accuracy and precision in quantitative NMR, GC-MS, and LC-MS measurements, compensating for extraction and ionization variability in sample analysis.
- Deuterium-labeled internal standard for NMR, GC-MS, and LC-MS quantitation.
- Isotope composition reflected in molecular formula C13H6D5Cl2NO2.
- Molecular weight 289.17.
- Purity >95.0% (HPLC) as stated by supplier listings.
- Supplied as a small research-grade vial (5 MG) for analytical use.
- Store under conditions specified on the certificate of analysis.
Medchemexpress LLC Glycine-13C2,15N | 211057-02-2 | MFCD00083979 | 99.9% | 78.05 g/mol | 13C2H515NO2 | 50mg
Glycine-13C2 15N is the 13C- and 15N-labeled Glycine Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors
Medchemexpress LLC L-Valine-d1 | 77257-03-5 | 118.15 | 25 MG
L-Valine-d1 is a deuterium-labeled version of L-Valine. L-Valine is a nonlinear semiorganic material that can cause lipid peroxidation and malondialdehyde (MDA) accumulation, and it has inhibitory activity against cyanobacteria. It also inhibits multidrug-resistant bacteria by activating the PI3K/Akt signaling pathway and inhibiting arginase.
- Can be used as a tracer and as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS.
- Stable heavy isotope where hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during drug development.
- Deuteration can influence the pharmacokinetic and metabolic profiles of drugs.
Cayman Chemical 14 15Leukotriene D4
A unique LT with weak contractile activity on both guinea pig ileum and pulmonary parenchyma compared to 5-LO-derived LTs; increases vascular permeability of human endothelial cell monolayers with similar potency to that of 5-LO-derived LTs
Cayman Chemical HypoxnthIn-d4 10mg
An internal standard for the quantification of hypoxanthine by GC- or LC-MS
Medchemexpress LLC Dehp-d38 | 352431-42-6 | 5 MG
DEHP-d38 is the deuterium labeled DEHP, which is an endogenous metabolite. This compound is useful as a tracer and as an internal standard for quantitative analysis.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, primarily as tracers for quantitation during the drug development process.
- Deuteration has the potential to influence the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC ((2-(6-Amino-9H-purin-9-yl)ethoxy)methyl)phosphonic acid-d4 | 1190021-70-5 | 98.7% | 2.5 MG
Adefovir-d4 is the deuterium labeled Adefovir, an adenosine monophosphate analog antiviral agent. After intracellular conversion to Adefovir diphosphate, it inhibits HBV DNA polymerase, with an IC50 of 0.7 μM against HBV in the HepG2.2.15 cell line. It exhibits good antiviral activity against several viruses, including HBV and herpesviruses.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporation of stable heavy isotopes into drug molecules can affect pharmacokinetic and metabolic profiles.
Cayman Chemical MelatonIn-d4 500ug
An internal standard for the quantification of melatonin by GC- or LC-MS